Post-finasteride Syndrome: A Review of Current Literature

Than et al., 2018

The occurrence of persistent adverse sexual, physical, neurological, and psychiatric side effects after 5α-reductase inhibitor is well supported by the existing data.
— Than et al.

Than et al. reviewed existing literature, including the symptom profile comprising physical changes, sexual dysfunction, and neurological and psychiatric changes as a lasting result of finasteride use.

They conclude that the existing evidence well supports the existence of persistent sexual, physical, neurological and central effects following 5alpha reductase inhibitor exposure, and that a growing understanding of the constellation of symptoms describing PFS should allow prescribers to better evaluate the risk and benefit of prescription.

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The Post-finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption

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The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men’s Health