Androgen Levels and Semen Parameters Among Former Users of Finasteride With Persistent Sexual Adverse Effects

Irwig, 2014

Further research is needed on the subset of men who may be susceptible to 5α-reductase inhibitors.
— Irwig

Serum androgen levels and semen parameters in 24 PFS patients were reported. 13% were found to have low total testosterone and 13% had low serum DHT. Mean serum androgen levels were close to other studies and could not explain the persistent symptoms.

16% (3 of 19) had severe oligospermia, whereas this finding would be expected in 3% of fertile-age men.

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Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-analysis

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A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long Term Side Effects after Finasteride Discontinuation